Key Mechanisms in Lysosome Stability, Degradation and Repair
Some viruses can impair the lysosome directly, or compromise lysosome stability through interaction with lysosome membrane components through mechanisms such as pore insertion, large-scale membrane disruption or lipid modification respectively. 88 Although not damaging the lysosome directly, Hepatitis C virus escapes lysosomal degradation by ...
In many instances this situation prevents the identification of specific protease substrates and hinders the understanding of the compensatory networking of proteases in the acidic cellular compartment.
Nonalcoholic fatty liver disease The SomaScan Assay can be used to detect biomarkers associated with nonalcoholic steatohepatitis and nonalcoholic fatty liver disease.
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